{"id":7762,"date":"2016-04-07T14:58:24","date_gmt":"2016-04-07T14:58:24","guid":{"rendered":"http:\/\/folicplus.rs\/en\/?p=7762"},"modified":"2016-04-07T14:58:24","modified_gmt":"2016-04-07T14:58:24","slug":"better-bioavailability-proven-active-folates-folicplus","status":"publish","type":"post","link":"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/","title":{"rendered":"Better bioavailability proven for active folates in FolicPlus\u00ae"},"content":{"rendered":"<p>Folates play a major role in stopping the neurological malfunction in children, and cardiovascular issues during development. Folate supplementation is recommended, especially in women in their reproductive period, with the goal of prevention neural tube defects development during pregnancy.<\/p>\n<p>At this moment, only synthetically derived folate forms are available, while products containing calcium salts of folates are rare, and <u>ONLY FolicPlus<sup>\u00ae<\/sup> contains the newest, 4<sup>th<\/sup> \u00a0generation form of active folates.<\/u><\/p>\n<p>The main goal of this research was to compare substance bioavailability between folates from FolicPlus<sup>\u00ae<\/sup> and other folate sources available.<\/p>\n<p><strong>METHOD: \u00a0<\/strong>Active folate (5-MTHF) form level was measured from blood samples via HPLC.<\/p>\n<p><strong>PARAMETERS: <\/strong>Mayor pharmacokinetic parameters were calculated (C<sub>max<\/sub>, t<sub>max<\/sub>, AUC).<\/p>\n<p><strong>REZULTS<\/strong>: It has been shown that a maximum concentration of active folates came from FolicPlus<sup>\u00ae<\/sup> supplements, that reached a \u00a0<strong><u>3.1 times higher level<\/u><\/strong> than any synthetic form of folic acid (281.5 \u00b1 135.7 ng \/ mL), and a \u00a01.8 times higher level than Ca-salts of folate (486.8\u00b1184.1 ng\/mL).<\/p>\n<p>FolicPlus<sup>\u00ae<\/sup> sources active folates remain up to <strong><u>9.7 times longer in blood<\/u><\/strong> in comparison to synthetic folic acid (114,7 ng \/ ml \u2219 h) and 1.12 times longer than Ca-salt of folates (997.6 ng\/mL \u2219 h).<\/p>\n<p><strong>CONCLUSION:\u00a0\u00a0 <\/strong><\/p>\n<p><strong>FolicPlus<sup><sup>\u00ae<\/sup><\/sup> has been proven to have higher bioavailability in comparison to every other folate and folic acid forms available.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Folates play a major role in stopping the neurological malfunction in children, and cardiovascular issues during development. Folate supplementation is recommended, especially in women in their reproductive period, with the goal of prevention neural tube defects development during pregnancy. At this moment, only synthetically derived folate forms are available, while products containing calcium salts of<\/p>\n","protected":false},"author":1,"featured_media":7755,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[313,312],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Better bioavailability proven for active folates in FolicPlus\u00ae &ndash; Folicplus+<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Better bioavailability proven for active folates in FolicPlus\u00ae &ndash; Folicplus+\" \/>\n<meta property=\"og:description\" content=\"Folates play a major role in stopping the neurological malfunction in children, and cardiovascular issues during development. Folate supplementation is recommended, especially in women in their reproductive period, with the goal of prevention neural tube defects development during pregnancy. At this moment, only synthetically derived folate forms are available, while products containing calcium salts of\" \/>\n<meta property=\"og:url\" content=\"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/\" \/>\n<meta property=\"og:site_name\" content=\"Folicplus+\" \/>\n<meta property=\"article:published_time\" content=\"2016-04-07T14:58:24+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/folicplus.rs\/wp-content\/uploads\/2016\/04\/Ve\u0107a-Bioraspolo\u017eivost-Aktivnog-Folata.png\" \/>\n\t<meta property=\"og:image:width\" content=\"750\" \/>\n\t<meta property=\"og:image:height\" content=\"418\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"sKadmin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"sKadmin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/\",\"url\":\"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/\",\"name\":\"Better bioavailability proven for active folates in FolicPlus\u00ae &ndash; Folicplus+\",\"isPartOf\":{\"@id\":\"https:\/\/folicplus.rs\/#website\"},\"datePublished\":\"2016-04-07T14:58:24+00:00\",\"dateModified\":\"2016-04-07T14:58:24+00:00\",\"author\":{\"@id\":\"https:\/\/folicplus.rs\/#\/schema\/person\/64004b567c2ff87ccb3792783a6e3f96\"},\"breadcrumb\":{\"@id\":\"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/folicplus.rs\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Better bioavailability proven for active folates in FolicPlus\u00ae\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/folicplus.rs\/#website\",\"url\":\"https:\/\/folicplus.rs\/\",\"name\":\"Folicplus+\",\"description\":\"Aktivni folat\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/folicplus.rs\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/folicplus.rs\/#\/schema\/person\/64004b567c2ff87ccb3792783a6e3f96\",\"name\":\"sKadmin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/folicplus.rs\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/83d63fa54fc98f336f1aacf14edc55bf?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/83d63fa54fc98f336f1aacf14edc55bf?s=96&d=mm&r=g\",\"caption\":\"sKadmin\"},\"url\":\"https:\/\/folicplus.rs\/en\/author\/skadmin\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Better bioavailability proven for active folates in FolicPlus\u00ae &ndash; Folicplus+","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/folicplus.rs\/en\/better-bioavailability-proven-active-folates-folicplus\/","og_locale":"en_US","og_type":"article","og_title":"Better bioavailability proven for active folates in FolicPlus\u00ae &ndash; Folicplus+","og_description":"Folates play a major role in stopping the neurological malfunction in children, and cardiovascular issues during development. 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